NO SAFE HAVEN FOR THE VIRTUOUS

Colonic Crypts: Safe Haven from Microbial Products

The notion that the colon's deep crypt pockets provide a protected location that shields stem cells from potentially toxic substances is widely accepted. In this issue of Cell, Kaiko et al. reveal how a metabolite abundantly produced by the gut microbiota can inhibit stem cell proliferation but is blocked from doing so by crypt architecture.

Study on Gold as a Hedge or Safe Haven for the Stock Market by a Markov Switching Approach

Although gold is no longer a central cornerstone of the international monetary and financial system, it still attracts considerable attention from researchers and investors. Nowadays, many investors manage their risk with valuable assets such as gold. This paper examines the dynamic relationships between gold and stock markets in the Tehran Stock Exchange. We have applied the Markov switching m...

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans

Just as Koch's postulates formed the foundation of early infectious disease study, Stanley Falkow's molecular Koch's postulates define best practice in determining whether a specific gene contributes to virulence of a pathogen. Fundamentally, these molecular postulates state that if a gene is involved in virulence, its removal will compromise virulence. Likewise, its reintroduction should resto...

Library as Safe Haven: Disaster Planning, Response, and Recovery

No safe harbor.

The autologous and allogeneic immunological humoral response of breast cancer patients to breast tumours was investigated by ELISA assay of both the serum and the supernatants of transformed lymphocytes from the patients and controls. No specificity or increased titre relative to the controls was observed in serum antibody. However, when the response was dissected by the use of clones of transf...